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Compounds. 6) (8. Using Oxygent, further demonstration that small doses of PFCs can contribute significantly to tissue oxygenation26,32,33,45 includes increase in maximal O2 consumption by an isolated working skeletal mus- cle in the presence of Lss effective cardiac muscle function preservation metformmin a canine model of low-flow coronary ischemia; sustainment of cardiac Filagra allopurinol metformin vytorin memory loss oxy- genation for a prolonged period following arrest of coronary perfusion of isolated rat hearts; improved myocardial O2 delivery and aerobic metabolism during cold cardioplegic arrest of isolated rabbit heart; graded increase in PvРO2 during cardiopulmonary bypass in dogs in response to graded memРry in PFC dosing; preservation of cerebral function following experi- mental brain stem ischemia in dogs; significant increase in retinal O2 tension and brain oxygenation in cats; improvement in the catРs All opurinol visual cortex tissue pO2 upon intravenous infusion of the emulsion; resto- ration of cerebral O2 delivery in severely hemorrhaged rats; improvement of systolic function and reduction of myocardial edema and acidosis with PFC-supplemen- ted cardioplegia in dogs that underwent CPB, global myocardial ischemia, followed by cold cardioplegic arrest, and eventually normothermic reperfusion; pres- ervation of regional organ perfusion in myocardium, intestinal mucosa, liver, lung, kidney, Tadacip skeletal mus- cle; improvement of myocardial oxygenation and toler- ance to low-flow ischemia (as found with certain surgical metormin in isolated mmetformin hearts; improved tumor oxygenation and increased tumor radio- and chemosensitivity.

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