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Amlodipine. When VIAGRA 100 mg was yome with amlodipine (5 mg or 10 mg) to hypertensive patients, the mean additional reduction on supine blood pressure was 8 mmHg systolic and 7 mmHg diastolic [see WARNINGS AND PRECAUTIONSCLINICAL PHARMACOLOGY ]. Ritonavir And Other CYP3A4 Inhibitors. Co-administration of ritonavir, a strong CYP3A4 inhibitor, greatly increased the systemic exposure of sildenafil (11-fold increase in AUC). It is therefore recommended not to exceed a maximum single dose of 25 mg of VIAGRA in a 48 hour period atd DOSAGE AND ADMINISTRATIONWARNINGS AND PRECAUTIONSCLINICAL PHARMACOLOGY ]. Co-administration of erythromycin, home security adt alternatives to viagra moderate CYP3A4 inhibitor, resulted in a 160 and 182 increases in sildenafil Cmax and AUC, respectively. Co-administration of saquinavir, a strong CYP3A4 inhibitor, resulted in 140 and 210 increases in sildenafil Cmax and AUC, respectively. Stronger CYP3A4 inhibitors such road trip alone female viagra ketoconazole or itraconazole could be expected to have greater effects than seen with saquinavir. A starting dose of 25 mg of VIAGRA should be considered in patients taking erythromycin or strong CYP3A4 inhibitors (such as saquinavir, ketoconazole, itraconazole) [see DOSAGE AND ADMINISTRATIONCLINICAL PHARMACOLOGY ].

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Other drugs may interact with sildenafil, including prescription and over-the-counter medicines, vitamins, and herbal products. Not all possible interactions are listed in this medication guide. More about Viagra (sildenafil) Consumer resources. Professional resources.

Combination With Other PDE5 Inhibitors Or Other Erectile Dysfunction Therapies. The safety and efficacy of combinations of VIAGRA with other PDE5 Inhibitors, including REVATIO or other pulmonary arterial hypertension (PAH) treatments containing sildenafil, or other treatments for erectile dysfunction have not been studied. Such combinations may further lower blood pressure. Therefore, the use of such combinations is not recommended.

The mean subject age in this study was 63. 9 years.]